Most cases of thyroid storm occur following a precipitating event or intercurrent illness. Thyroid storm is a dreaded, fortunately rare complication of a very common disorder. Although some authors have attributed this improvement, in part, to a relaxation of the diagnostic criteria for thyroid storm, it more likely represents improvements in early recognition and the beneficial effects of the serial addition of antithyroid, corticosteroid, and antiadrenergic therapies to the treatment of this disorder. More recent series have yielded fatality rates between 20% and 50%. Although important strides in recognition and therapy have significantly reduced the mortality in this disorder from the nearly 100% fatality rate noted by Lahey, survival is by no means guaranteed.
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